Cultivating an atmosphere of collaboration, camaraderie, and diversity

Philosophy

We aim to ask clinically relevant questions and to answer them with teamwork and scientific rigor.

The Hernando Lab is working to dissect the molecular basis of cancer metastasis, using melanoma as a model.

We apply a multi-pronged approach based on the analysis of human samples, in vitro and in vivo models and cutting-edge cell, imaging and molecular biology techniques to discover fundamental mechanisms underlying tumor progression. This strategy allows us to uncover novel, in- depth molecular mechanisms, which are relevant to patients and have potential for clinical application. Through the past 12 years we have uncovered new roles for noncoding RNA, transcriptional programs and protein glycosylation into melanoma initiation and metastasis, which have been published in prestigious journals such as Journal of National Cancer Institute, Nat Cell Biol, Cell reports, and Cancer Cell. We have been uninterruptedly funded by NCI/NIH, Department of Defense and peer-reviewed programs of the Melanoma Research Alliance and American Cancer Society.

We train our lab members to become the next-generation of molecular and cancer biologists, empowered with the intellectual and technical skills that will allow them to continue leading impact and innovation in translational research. Our goal is to help each and every lab member enjoy life in the lab while fulfilling their maximum potential as scientists. Our team includes a mix of students (undergrads, MS, PhD, and MD-PhD) from NYU downtown and NYU School of Medicine, postdoctoral scientists, staff scientists, and research technicians.

We welcome new ideas and encourage risk taking and exploration, as we are convinced that it is the only path to innovation and high impact discoveries.
We also strive to make the process of doing science fun. Most projects in the lab are structured around small teams. This makes life in lab more enjoyable and pushes projects forward faster than with one person going it alone. Above all, we value hard work, motivation, resilience and drive because often success comes only after trying many ideas and enduring through failures. We promote a culture of high standards, reproducibility and rigor; never letting the pace of discoveries compromise quality. We welcome a diversity of individuals from multiple cultural backgrounds, which makes the lab a lively environment and enriches us as both humans and scientists. We provide advice and support to our trainees in the variety of career choices they contemplate after leaving the lab. 
Our students have successfully competed for F30 fellowships. Many postdoctoral scientists have obtained postdoctoral fellowships, including the EMBO Fellowship, the Human Frontiers Science Program Fellowship, or the National Cancer Center fellowship. Our senior scientists have received career awards from the New York Stem Cell Foundation, the Department of Defense, the Harry Lloyd Charitable Trust and the NIH K22 award. Some of our former trainees are now Principal Investigators at prestigious institutions, such as the VHIO in Barcelona (Spain) and TIGET in Milan (Italy). 

Team Members

Eva Hernando

Eva obtained her PhD in Sciences (Molecular Biology) at the Universidad Autónoma (Madrid, Spain) in 1999. She conducted her post-doctoral studies at Memorial Sloan-Kettering Cancer Center in New York City and Cold Spring Harbor laboratories, co-supervised by Carlos Cordon-Cardo, MD PhD, and Scott W. Lowe, PhD. She joined the Department of Pathology at NYU School of Medicine in 2006 where she is currently a tenured professor and assistant dean for research integration. She has served as vicechair for the Department of Pathology and associate director for basic science for the Perlmutter Cancer Center, an NCI-designated Cancer Center. She has published more than 80 peer-reviewed articles, including reports at Nature, Nature Medicine, Nature Cell Biology and Cancer Cell. She is a permanent member of the Cancer Molecular Pathobiology [CAMP] NIH Study Section. In her free time, she enjoys traveling and visiting NYC parks and museums with her husband and two children.

Grace Levinson

Grace is an Undergraduate Research Assistant in the Hernando Laboratory interested in studying the mechanisms behind brain metastasis. She is pursuing a B.S. in Biology at New York University and plans on pursuing an MD/PhD after graduating. Currently, Grace is working to understand the mechanisms behind melanoma brain metastasis and the interaction of melanoma cells with the brain microenvironment. Outside of research, Grace enjoys going to movies and finding the best tiramisus in New York City. 

Kevin Kleffman

Kevin is an MD/PhD Candidate in the Hernando Laboratory interested in investigating the mechanisms behind melanoma brain metastasis and the interactions of melanoma cells with the brain microenvironment. Outside of research, Kevin enjoys playing tennis and baking desserts for the lab. 

Alcida Karz

Allie is a third year MD/PhD student investigating mechanisms of melanoma brain metastasis. Allie initially joined the Hernando lab as a member of the NYU Summer Undergraduate Research Program in 2016. After graduating from Duke University with a B.S. in Biology and completing her first half of medical school, circular RNAs were still on her mind, so she re-joined the lab for her PhD in spring 2019. Besides pipetting small volumes of liquid from one tube to another, Allie’s passions include breakfast food and rescue dogs.

Rana Moubarak

Rana is an Instructor of the Department of Pathology. Using a translational research approach, she is interested in understanding the molecular basis of cancer progression and metastasis. Currently, Rana’s goal consists in a deeper understanding of epigenetic mechanisms favoring the survival and invasiveness of cancer cells, as well as the potential use of epigenetic regulators as biomarkers of prognosis and/or therapeutic targets. Born and raised in Lebanon, Rana performed her Ph.D. in Biology at the University Paris VI and Institut Pasteur, France, followed by a postdoctoral training at the Vall d’Hebron Institute in Barcelona, Spain. Outside of the lab, Rana enjoys hiking, attending the ballet, and eating plantain chips with her friends.

Praveen Agrawal

Praveen is an Associate Research Scientist for the Hernando laboratory interested in understanding the role of protein glycosylation in cancer biology. Praveen received M.Sc. in Biotechnology from Jiwaji University, Gwalior, India and Ph.D. in Biotechnology from Institute of Genomics and Integrative Biology (CSIR), Delhi, India. Currently, Praveen is working on a project to identify novel carbohydrate epitopes and glycogenes play role in progression, establishment and tropism of melanoma metastasis. Outside of research, Praveen enjoys gardening.

Victoria Osorio Vasquez

Victoria is a PhD Candidate in the Pacold and Hernando laboratories. She is working toward discovering metabolic vulnerabilities in melanoma in order to create novel therapies to impede brain metastasis. Alongside her work in the laboratory, Victoria serves as Student Diversity Initiative Co-facilitator and is focused on developing a sense of community amongst graduate students that fosters diversity and inclusion in science. When she isn’t in the lab, she enjoys dancing, cooking, and hanging out with her dog.

Gillian Baptiste

Gillian is a post-doc working on improving our understanding of the development of melanoma brain metastases. After graduating with a BA in biochemistry from Bowdoin College, Gillian obtained her MD at Emory University School of Medicine.  She began her residency in general surgery at NYU in 2016.  After completing three years of training, Gillian elected to take time away from clinical work to pursue research full time in the Hernando lab.  Following her research years, Gillian plans to complete residency and pursue a fellowship in abdominal transplant surgery. Outside of work, Gillian enjoys cooking, spending time with family, and hiking.

Arman Alberto Sorin Shadaloey

Sorin is a Research Scientist that took time away from his general surgery residency to better understand the mechanisms of melanoma metastasis. He believes this work will help him foster an accelerated collaborative environment between surgical oncology and basic research in his future career in academia. Sorin is an MD/MSc graduate of Carol Davila Medicine and Pharmacy University, Bucharest, Romania. When not thinking about his in vivo mouse experiments, he enjoys the outdoors, visual arts and watching tennis. 

Andrey Rubanov

Andrey is a PhD student interested in developing prognostic models for early-stage melanoma metastatic dissemination. He received his bachelor’s in Human Biology from UCSD, as well a master’s in Biology studying honey bee innate immune priming and gut microbiome host-pathogen interactions. Subsequently he spent 3 years as a technician at Sanford Burnham Prebys Medical Discovery Institute performing high-throughput screening and molecular profiling of small molecule cGAS/STING agonists in primary human dendritic cells for enhanced antigen presentation in the tumor microenvironment. Outside of the lab Andrey enjoys reading and spending time in nature.

Nicole Eskow

Nicole is a third year MD/PhD student interested in dissecting the interactions between the immune system and melanoma brain metastases. She graduated with a B.S. and M.S. in Molecular, Cellular and Developmental Biology from Yale University in 2019. Outside of lab, Nicole enjoys baking and knitting, and she is a certified fitness instructor.

Alumni

Former Postdocs

Doug Hanniford, PhD

Doug was a graduate student, post doc, and then instructor in the Hernando laboratory. His focus was on elucidating functions and mechanisms of circular RNA in melanoma metastasis.

Miguel F. Segura, PhD.

Current position: Principal Investigator at Vall d’Hebron Research Institute (VHIR); Barcelona, Spain

Maria V. Guijarro, PhD

Current position: Senior Research Scientist at University of Florida; Gainesville, FL

Chanh Huynh, MD PhD

Current position: Medical Oncologist at Cancer Care Associates of York; Hershey, PA

Raffaella DiMicco PhD

Current position: Principal Investigator at TIGET Institute; Milan, Italy


Verónica Davalos Vega, PhD

Current position: Research Associate, Josep Carreras Institute, Barcelona, Spain

Luca Paoluzzi, MD


Current position: Director, Sarcoma/Melanoma Medical Oncology Program at Montefiore and Assistant Professor, Department of Oncology at Albert Einstein Medical School, New York.

Alfredo Floristán, PhD

Current position: Clinical scientist at ROVI; Madrid, Spain

Gillian Baptiste, MD

Former Grad Students

Ovaun Latouche

Ovaun was a first year Masters student in the Hernando laboratory. He is interested in studying the epistatic relationship between oncogenes in melanoma progression.

Laura S. Danielson, PhD;

Sackler Institute of Biomedical Research, NYUSoM, NY.
Current: Senior Science Communications Manager at Cancer Research UK

Avital Gaziel, PhD

Sackler Institute of Biomedical Research, NYUSoM, NY.
Current: Co-founder; Head of Medical Affairs at Trialjectory

Lisa Koetz-Ploch, PhD;

Sackler Institute of Biomedical Research, NYUSoM, NY.
Current position: Associate Medical Director at TrialJectory

Barbara Fontanals-Cirera, PhD

Sackler Institute of Biomedical Research, NYUSoM, NY.
Current position: Associate Medical Director at TrialJectory

Alejandro Ulloa-Morales, PhD

Sackler Institute of Biomedical Research, NYUSoM, NY.
Current position: Post-doc, Max Plank Institute, Germany

Gabriela Berzoti, PhD

University of Sao Paolo, Brazil
Current position: Post-doc, University of Sao Paolo, Brazil

Jiexi Li, MS

New York University, NY
Current position: Graduate Research Assistant, MD Anderson Cancer Center UTHealth

Former Visiting Grad Students

Pilar Gonzalez-Gomez, PhD

Instituto de Salud Carlos III, Madrid, Spain

Sebastian Stefan, MS

University of Vienna, Austria

Silvia Alvarez, PhD

Instituto de Investigaciones Biomédicas, Madrid, Spain

Lorena Arranz, PhD

Universidad Complutense, Madrid, Spain

Marc Coussens, PhD

Sackler Institute of Biomedical Research, NYUSoM, NY.

Maria Diaz-Martinez, PhD

Centro Superior Investigaciones Cientificas (CSIC), Madrid Spain

Karin Lijia, PhD

Sackler Institute of Biomedical Research, NYUSoM, NY.

Former Research Technicians

Richard Von Itter

Richard was a Research Technician in the Hernando laboratory interested in studying regulators of melanoma metastasis and immunotherapy. He currently is getting his PhD at NYU.

Silvia Menendez, MS

Xavier Jirau-Serrano

Elena Sokolova, MD.

Claudia D. Lovell

Diana Arbibay, BS

Former Undergraduates

Claudia D. Lovell

Ana de Pablos Aragoneses

Ainhoa Ruiz Iglesias

Ines Delclaux

Francisco Galan

Elena Garcia-Castellanos

Vanessa Ortiz Barahona

Stephanie K. Yuen

Olivia Maguire

Vivian Low

Lab Life

Hernando Lab Team, Lab Life
Hernando Lab Team, Lab Life
Hernando Lab Team, Lab Life
Hernando Lab Team, Lab Life
Hernando Lab Team, Lab Life
Hernando Lab Team, Lab Life
Hernando Lab Team, Lab Life

Join

Thank you for your interest in our lab! To apply, please send an email with the following: 

 

Your CV with a list of publications

A short summary of your present and future research interests

For postdoc candidates only: A list of three references with names, phone numbers and email addresses