Publications - 2013

Hedgehog pathway blockade inhibits melanoma cell growth in vitro and in vivo

O’Reilly, K. E., de Miera, E. V., Segura, M. F., Friedman, E., Poliseno, L., Han, S. W., Zhong, J., Zavadil, J., Pavlick, A., Hernando, E., & Osman, I. (2013). Pharmaceuticals (Basel, Switzerland), 6(11), 1429–1450.

PMID: 24287465

Clinicopathological characteristics at primary melanoma diagnosis at risk factors for brain metastasis

Qian, M., Ma, M. W., Fleming, N. H., Lackaye, D. J., Hernando, E., Osman, I., & Shao, Y. (2013). Melanoma research, 23(6), 461–467.

PMID: 24165034

Development and Characterization of a Clinically Relevant Mouse Model of Melanoma Brain Metastasis

Morsi, A., Gaziel-Sovran, A., Cruz-Munoz, W., Kerbel, R. S., Golfinos, J. G., Hernando, E., & Wadghiri, Y. Z. (2013). Pigment cell & melanoma research, 26(5), 743–745.

PMID: 23647875

BRD4 sustains proliferation and represents a new target for epigenetic therapy in melanoma

Segura, M. F., Fontanals-Cirera, B., Gaziel-Sovran, A., Guijarro, M. V., Hanniford, D., Zhang, G., González-Gomez, P., Morante, M., Jubierre, L., Zhang, W., Darvishian, F., Ohlmeyer, M., Osman, I., Zhou, M. M., & Hernando, E. (2013). Cancer research, 73(20), 6264–6276.

PMID: 23950209

Dual Pten/p53 suppression promotes sarcoma progression by triggering Notch signaling

Guijarro, M. V., Dahiya, S., Danielson, L. S., Segura, M. F., Vales-Lara, F. M., Menendez, S., Popiolek, D., Mittal, K., Wei, J. J., Zavadil, J., Cordon-Cardo, C., Pandolfi, P. P., & Hernando, E. (2013). The American journal of pathology, 182(6), 2015–2027.

PMID: 23708211

FBH1 protects melanocytes from transformation and is deregulated in melanomas

Jeong, Y. T., Cermak, L., Guijarro, M. V., Hernando, E., & Pagano, M. (2013). Cell cycle (Georgetown, Tex.), 12(7), 1128–1132.

PMID: 23466708

Inactivation of Patched1 in Mice Leads to Development of Gastrointestinal Stromal-Like Tumors That Express Pdgfrα but Not Kit

Pelczar, P., Zibat, A., van Dop, W. A., Heijmans, J., Bleckmann, A., Gruber, W., Nitzki, F., Uhmann, A., Guijarro, M. V., Hernando, E., Dittmann, K., Wienands, J., Dressel, R., Wojnowski, L., Binder, C., Taguchi, T., Beissbarth, T., Hogendoorn, P. C., Antonescu, C. R., Rubin, B. P., … Hahn, H. (2013). Gastroenterology, 144(1), 134–144.e6.

PMID: 23041331

Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis

Danielson, L. S., Park, D. S., Rotllan, N., Chamorro-Jorganes, A., Guijarro, M. V., Fernandez-Hernando, C., Fishman, G. I., Phoon, C. K., & Hernando, E. (2013). FASEB journal: official publication of the Federation of American Societies for Experimental Biology, 27(4), 1460–1467.

PMID: 23271053