Publications - 2020

Human genes differ by their UV sensitivity estimated through analysis of UV-induced silent mutations in melanoma

Gorlov, Ivan P; Amos, Christopher I; Tsavachidis, Spiridon; Begg, Colin; Hernando, Eva; Cheng, Chao; Shen, Ronglai; Orlow, Irene; Luo, Li; Ernstoff, Marc S; Parker, Joel; Thomas, Nancy E; Gorlova, Olga Y; Berwick, Marianne. Hum Mutat. 2020 Jul 9. doi: 10.1002/humu.24078. Online ahead of print.

PMID: 32643855

Limited environmental serine and glycine confer brain metastasis sensitivity to PHGDH Inhibition

Ngo B, Kim E, Osorio-Vasquez V, Doll S, Bustraan S, Liang RJ, Luengo A, Davidson SM, Ali A, Ferraro GB, Fischer GM, Eskandari R, Kang DS, Ni J, Plasger A, Rajasekhar VK, Kastenhuber ER, Bacha S, Sriram RK, Stein BD, Bakhoum SF, Snuderl M, Cotzia P, Healey JH, Mainolfi N, Suri V, Friedman A, Manfredi M, Sabatini DM, Jones DR, Yu M, Zhao JJ, Jain RK, Keshari KR, Davies MA, Vander Heiden MG, Hernando E, Mann M, Cantley LC, Pacold ME. Cancer Discov. 2020 Jun 22:CD-19-1228. doi: 10.1158/2159-8290.CD-19-1228.

PMID: 32571778

circSamd4 represses myogenic transcriptional activity of PUR proteins

Pandey, Poonam R; Yang, Jen-Hao; Tsitsipatis, Dimitrios; Panda, Amaresh C; Noh, Ji Heon; Kim, Kyoung Mi; Munk, Rachel; Nicholson, Thomas; Hanniford, Douglas; Argibay, Diana; Yang, Xiaoling; Martindale, Jennifer L; Chang, Ming-Wen; Jones, Simon W; Hernando, Eva; Sen, Payel; De, Supriyo; Abdelmohsen, Kotb; Gorospe, Myriam. Nucleic acids research. 2020.

PMID:

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

Hanniford, D., Ulloa-Morales, A., Karz, A., Berzoti-Coelho, M. G., Moubarak, R. S., Sánchez-Sendra, B., Kloetgen, A., Davalos, V., Imig, J., Wu, P., Vasudevaraja, V., Argibay, D., Lilja, K., Tabaglio, T., Monteagudo, C., Guccione, E., Tsirigos, A., Osman, I., Aifantis, I., & Hernando, E. (2020). Cancer cell, 37(1), 55–70.

PMID: 31935372

Functional analysis of RPS27 mutations and expression in melanoma

Floristán, A., Morales, L., Hanniford, D., Martinez, C., Castellano-Sanz, E., Dolgalev, I., Ulloa-Morales, A., Vega-Saenz de Miera, E., Moran, U., Darvishian, F., Osman, I., Kirchhoff, T., & Hernando, E. (2020). Pigment cell & melanoma research, 33(3), 466–479.

PMID: 31663663