Publications

Limited environmental serine and glycine confer brain metastasis sensitivity to PHGDH Inhibition

Ngo B, Kim E, Osorio-Vasquez V, Doll S, Bustraan S, Liang RJ, Luengo A, Davidson SM, Ali A, Ferraro GB, Fischer GM, Eskandari R, Kang DS, Ni J, Plasger A, Rajasekhar VK, Kastenhuber ER, Bacha S, Sriram RK, Stein BD, Bakhoum SF, Snuderl M, Cotzia P, Healey JH, Mainolfi N, Suri V, Friedman A, Manfredi M, Sabatini DM, Jones DR, Yu M, Zhao JJ, Jain RK, Keshari KR, Davies MA, Vander Heiden MG, Hernando E, Mann M, Cantley LC, Pacold ME. Cancer Discov. 2020 Jun 22:CD-19-1228. doi: 10.1158/2159-8290.CD-19-1228.

PMID: 32571778

circSamd4 represses myogenic transcriptional activity of PUR proteins

Pandey, Poonam R; Yang, Jen-Hao; Tsitsipatis, Dimitrios; Panda, Amaresh C; Noh, Ji Heon; Kim, Kyoung Mi; Munk, Rachel; Nicholson, Thomas; Hanniford, Douglas; Argibay, Diana; Yang, Xiaoling; Martindale, Jennifer L; Chang, Ming-Wen; Jones, Simon W; Hernando, Eva; Sen, Payel; De, Supriyo; Abdelmohsen, Kotb; Gorospe, Myriam. Nucleic acids research. 2020.

PMID:

Epigenetic Silencing of CDR1as Drives IGF2BP3-Mediated Melanoma Invasion and Metastasis

Hanniford, D., Ulloa-Morales, A., Karz, A., Berzoti-Coelho, M. G., Moubarak, R. S., Sánchez-Sendra, B., Kloetgen, A., Davalos, V., Imig, J., Wu, P., Vasudevaraja, V., Argibay, D., Lilja, K., Tabaglio, T., Monteagudo, C., Guccione, E., Tsirigos, A., Osman, I., Aifantis, I., & Hernando, E. (2020). Cancer cell, 37(1), 55–70.

PMID: 31935372

Functional analysis of RPS27 mutations and expression in melanoma

Floristán, A., Morales, L., Hanniford, D., Martinez, C., Castellano-Sanz, E., Dolgalev, I., Ulloa-Morales, A., Vega-Saenz de Miera, E., Moran, U., Darvishian, F., Osman, I., Kirchhoff, T., & Hernando, E. (2020). Pigment cell & melanoma research, 33(3), 466–479.

PMID: 31663663

A Leukocyte Infiltration Score Defined by a Gene Signature Predicts Melanoma Patient Prognosis

Zhao, Y., Schaafsma, E., Gorlov, I. P., Hernando, E., Thomas, N. E., Shen, R., Turk, M. J., Berwick, M., Amos, C. I., & Cheng, C. (2019). Molecular cancer research: MCR, 17(1), 109–119.

PMID: 30171176

Identification of gene expression levels in primary melanoma associated with clinically meaningful characteristics

Gorlov, I., Orlow, I., Ringelberg, C., Hernando, E., Ernstoff, M. S., Cheng, C., Her, S., Parker, J. S., Thompson, C. L., Gerstenblith, M. R., Berwick, M., & Amos, C. (2018). Melanoma research, 28(5), 380–389.

PMID: 29975213

Primary melanoma histologic subtype impacts melanoma specific survival and response to systemic therapy

Lattanzi, M., Lee, Y., Simpson, D., Moran, U., Darvishian, F., Kim, R. H., Hernando, E., Polsky, D., Hanniford, D., Shapiro, R., Berman, R., Pavlick, A. C., Wilson, M. A., Kirchhoff, T., Weber, J. S., Zhong, J., & Osman, I. (2019). Journal of the National Cancer Institute, 111(2), 180–188.

PMID: 29912415

Differential phosphorylation and N-terminal configuration of capsid subunits in parvovirus assembly and viral trafficking

Gil-Ranedo, J., Hernando, E., Valle, N., Riolobos, L., Maroto, B., & Almendral, J. M. (2018). Virology, 518, 184–194.

PMID: 29524834

miR-204-5p and miR-211-5p contribute to BRAF inhibitor resistance in melanoma

Díaz-Martínez, M., Benito-Jardón, L., Alonso, L., Koetz-Ploch, L., Hernando, E., & Teixidó, J. (2018). Cancer research, 78(4), 1017–1030.

PMID: 29229605

Lysyl oxidase-like 3 is required for melanoma cell survival by maintaining genomic stability

Santamaría, P. G., Floristán, A., Fontanals-Cirera, B., Vázquez-Naharro, A., Santos, V., Morales, S., Yuste, L., Peinado, H., García-Gómez, A., Portillo, F., Hernando, E., & Cano, A. (2018). Cell death and differentiation, 25(5), 935–950.

PMID: 29229995

Harnessing BET inhibitor sensitivity reveals AMIGO2 as a melanoma survival gene

Fontanals-Cirera, B., Hasson, D., Vardabasso, C., Di Micco, R., Agrawal, P., Chowdhury, A., Gantz, M., de Pablos-Aragoneses, A., Morgenstern, A., Wu, P., Filipescu, D., Valle-Garcia, D., Darvishian, F., Roe, J. S., Davies, M. A., Vakoc, C. R., Hernando, E., & Bernstein, E. (2017). Molecular cell, 68(4), 731–744.e9.

PMID: 29149598