BRD4 sustains proliferation and represents a new target for epigenetic therapy in melanoma

Segura, M. F., Fontanals-Cirera, B., Gaziel-Sovran, A., Guijarro, M. V., Hanniford, D., Zhang, G., González-Gomez, P., Morante, M., Jubierre, L., Zhang, W., Darvishian, F., Ohlmeyer, M., Osman, I., Zhou, M. M., & Hernando, E. (2013). Cancer research, 73(20), 6264–6276.

PMID: 23950209

Development and Characterization of a Clinically Relevant Mouse Model of Melanoma Brain Metastasis

Morsi, A., Gaziel-Sovran, A., Cruz-Munoz, W., Kerbel, R. S., Golfinos, J. G., Hernando, E., & Wadghiri, Y. Z. (2013). Pigment cell & melanoma research, 26(5), 743–745.

PMID: 23647875

Dual Pten/p53 suppression promotes sarcoma progression by triggering Notch signaling

Guijarro, M. V., Dahiya, S., Danielson, L. S., Segura, M. F., Vales-Lara, F. M., Menendez, S., Popiolek, D., Mittal, K., Wei, J. J., Zavadil, J., Cordon-Cardo, C., Pandolfi, P. P., & Hernando, E. (2013). The American journal of pathology, 182(6), 2015–2027.

PMID: 23708211

FBH1 protects melanocytes from transformation and is deregulated in melanomas

Jeong, Y. T., Cermak, L., Guijarro, M. V., Hernando, E., & Pagano, M. (2013). Cell cycle (Georgetown, Tex.), 12(7), 1128–1132.

PMID: 23466708

Cardiovascular dysregulation of miR-17-92 causes a lethal hypertrophic cardiomyopathy and arrhythmogenesis

Danielson, L. S., Park, D. S., Rotllan, N., Chamorro-Jorganes, A., Guijarro, M. V., Fernandez-Hernando, C., Fishman, G. I., Phoon, C. K., & Hernando, E. (2013). FASEB journal: official publication of the Federation of American Societies for Experimental Biology, 27(4), 1460–1467.

PMID: 23271053

Inactivation of Patched1 in Mice Leads to Development of Gastrointestinal Stromal-Like Tumors That Express Pdgfrα but Not Kit

Pelczar, P., Zibat, A., van Dop, W. A., Heijmans, J., Bleckmann, A., Gruber, W., Nitzki, F., Uhmann, A., Guijarro, M. V., Hernando, E., Dittmann, K., Wienands, J., Dressel, R., Wojnowski, L., Binder, C., Taguchi, T., Beissbarth, T., Hogendoorn, P. C., Antonescu, C. R., Rubin, B. P., … Hahn, H. (2013). Gastroenterology, 144(1), 134–144.e6.

PMID: 23041331

Serum microRNAs as biomarkers for recurrence in melanoma

Friedman, E. B., Shang, S., de Miera, E. V., Fog, J. U., Teilum, M. W., Ma, M. W., Berman, R. S., Shapiro, R. L., Pavlick, A. C., Hernando, E., Baker, A., Shao, Y., & Osman, I. (2012). Journal of translational medicine, 10, 155.

PMID: 22857597

Challenging the current paradigm of melanoma progression: brain metastasis as isolated first visceral site

Ma, M. W., Qian, M., Lackaye, D. J., Berman, R. S., Shapiro, R. L., Pavlick, A. C., Golfinos, J. G., Parker, E. C., Darvishian, F., Hernando, E., Shao, Y., & Osman, I. (2012). Neuro-oncology, 14(7), 849–858.

PMID: 22561799

Histology-specific microRNA alterations in melanoma

Poliseno, L., Haimovic, A., Segura, M. F., Hanniford, D., Christos, P. J., Darvishian, F., Wang, J., Shapiro, R. L., Pavlick, A. C., Berman, R. S., Hernando, E., Zavadil, J., & Osman, I. (2012). The Journal of investigative dermatology, 132(7), 1860–1868.

PMID: 22551973

MicroRNA-22 is induced by vitamin D and contributes to its antiproliferative, antimigratory and gene regulatory effects in colon cancer cells

Alvarez-Díaz, S., Valle, N., Ferrer-Mayorga, G., Lombardía, L., Herrera, M., Domínguez, O., Segura, M. F., Bonilla, F., Hernando, E., & Muñoz, A. (2012). Human molecular genetics, 21(10), 2157–2165.

PMID: 22328083