Publications

MiR-182 overexpression in tumourigenesis of high-grade serous ovarian carcinoma.

Liu, Z., Liu, J., Segura, M. F., Shao, C., Lee, P., Gong, Y., Hernando, E., & Wei, J. J. (2012). The Journal of pathology, 228(2), 204–215.

PMID: 22322863

The Novel Gamma Secretase Inhibitor RO4929097 Reduces the Tumor Initiating Potential of Melanoma

Huynh, C., Poliseno, L., Segura, M. F., Medicherla, R., Haimovic, A., Menendez, S., Shang, S., Pavlick, A., Shao, Y., Darvishian, F., Boylan, J. F., Osman, I., & Hernando, E. (2011). PloS one, 6(9), e25264.

PMID: 21980408

MiR-30b/30d regulation of GalNAc transferases enhances invasion and synthesis of the immunosuppressive cytokine IL-10 during metastasis

Gaziel-Sovran, A., Segura, M. F., Di Micco, R., Collins, M. K., Hanniford, D., Vega-Saenz de Miera, E., Rakus, J. F., Dankert, J. F., Shang, S., Kerbel, R. S., Bhardwaj, N., Shao, Y., Darvishian, F., Zavadil, J., Erlebacher, A., Mahal, L. K., Osman, I., & Hernando, E. (2011). Cancer cell, 20(1), 104–118.

PMID: 21741600

Clinical variables and primary melanoma characteristics predictive of the development of brain metastases and survival in melanoma patients

Zakrzewski, J., Geraghty, L. N., Rose, A. E., Christos, P. J., Mazumdar, M., Polsky, D., Shapiro, R., Berman, R., Darvishian, F., Hernando, E., Pavlick, A., & Osman, I. (2011). Cancer, 117(8), 1711–1720.

PMID: 21061370

Integrative genomics identifies molecular alterations that challenge the linear model of melanoma progression

Rose, A. E., Poliseno, L., Wang, J., Clark, M., Pearlman, A., Wang, G., Vega Y Saenz de Miera, E. C., Medicherla, R., Christos, P. J., Shapiro, R., Pavlick, A., Darvishian, F., Zavadil, J., Polsky, D., Hernando, E., Ostrer, H., & Osman, I. (2011). Cancer research, 71(7), 2561–2571.

PMID: 21343389

HMGA2 overexpression-induced ovarian surface epithelial transformation resembles high grade serous carcinoma through regulation of EMT genes

Wu, J., Liu, Z., Shao, C., Gong, Y., Hernando, E., Lee, P., Narita, M., Muller, W., Liu, J., & Wei, J. J. (2011). Cancer research, 71(2), 349–359.

PMID: 21224353

Regulation of HMGA1 expression by microRNA296 affects prostate cancer growth and invasion

Wei, J. J., Wu, X., Peng, Y., Shi, G., Basturk, O., Yang, X., Daniels, G., Osman, I., Ouyang, J., Hernando, E., Pellicer, A., Rhim, J. S., Melamed, J., & Lee, P. (2011). Clinical cancer research: an official journal of the American Association for Cancer Research, 17(6), 1297–1305.

PMID: 21138859

Efficient in vivo miRNA targeting of liver metastasis

Huynh, C., Segura, M. F., Gaziel-Sovran, A., Menendez, S., Darvishian, F., Chiriboga, L., Levin, B., Meruelo, D., Osman, I., Zavadil, J., Marcusson, E. G., & Hernando, E. (2011). Oncogene, 30(12), 1481–1488.

PMID: 21102518

Clinical relevance of SKP2 alterations in metastatic melanoma. Pigment Cell Melanoma Res

A.E. Rose, G. Wang, D. Hanniford, S Monni, T Tu, RL. Shapiro, RS. Berman, AC. Pavlick, M Pagano, F Darvishian, M Mazumdar, E Hernando, and I Osman.

24(1):197-206 (2011).

PMID: 20883453

The histone variant macroH2A suppresses melanoma progression through regulation of CDK8

Kapoor, A., Goldberg, M. S., Cumberland, L. K., Ratnakumar, K., Segura, M. F., Emanuel, P. O., Menendez, S., Vardabasso, C., Leroy, G., Vidal, C. I., Polsky, D., Osman, I., Garcia, B. A., Hernando, E., & Bernstein, E. (2010). Nature, 468(7327), 1105–1109.

PMID: 21179167