Publications
HMGA2 overexpression-induced ovarian surface epithelial transformation resembles high grade serous carcinoma through regulation of EMT genes
Wu, J., Liu, Z., Shao, C., Gong, Y., Hernando, E., Lee, P., Narita, M., Muller, W., Liu, J., & Wei, J. J. (2011). Cancer research, 71(2), 349–359.
PMID: 21224353
Regulation of HMGA1 expression by microRNA296 affects prostate cancer growth and invasion
Wei, J. J., Wu, X., Peng, Y., Shi, G., Basturk, O., Yang, X., Daniels, G., Osman, I., Ouyang, J., Hernando, E., Pellicer, A., Rhim, J. S., Melamed, J., & Lee, P. (2011). Clinical cancer research: an official journal of the American Association for Cancer Research, 17(6), 1297–1305.
PMID: 21138859
Efficient in vivo miRNA targeting of liver metastasis
Huynh, C., Segura, M. F., Gaziel-Sovran, A., Menendez, S., Darvishian, F., Chiriboga, L., Levin, B., Meruelo, D., Osman, I., Zavadil, J., Marcusson, E. G., & Hernando, E. (2011). Oncogene, 30(12), 1481–1488.
PMID: 21102518
Clinical relevance of SKP2 alterations in metastatic melanoma. Pigment Cell Melanoma Res
A.E. Rose, G. Wang, D. Hanniford, S Monni, T Tu, RL. Shapiro, RS. Berman, AC. Pavlick, M Pagano, F Darvishian, M Mazumdar, E Hernando, and I Osman.
24(1):197-206 (2011).
PMID: 20883453
The histone variant macroH2A suppresses melanoma progression through regulation of CDK8
Kapoor, A., Goldberg, M. S., Cumberland, L. K., Ratnakumar, K., Segura, M. F., Emanuel, P. O., Menendez, S., Vardabasso, C., Leroy, G., Vidal, C. I., Polsky, D., Osman, I., Garcia, B. A., Hernando, E., & Bernstein, E. (2010). Nature, 468(7327), 1105–1109.
PMID: 21179167
Profiling and Functional Analyses of MicroRNAs and Their Target Gene Products in Human Uterine Leiomyomas
J. Zavadil, H. Ye, Z. Liu, J. Wu, P. Lee, E. Hernando, P. Soteropoulos, GA Toruner, JJ Wei.
PLoS One, 5(8): e12362. (2010).
PMID: 20808773
A differentiation-based miRNA signature identifies leiomyosarcomas as a mesenchymal-stem cell related malignancy
L.S. Danielson, S. Menendez, C. Stephan-Otto Attolini, M.V. Guijarro, M. Bisogna, J.J. Wei, N.D. Socci, D.A. Levine, F. Michor and E. Hernando.
Am J Pathol. 177(2):908-17 (2010).
PMID: 20558575
MicroRNA signature predicts melanoma post-recurrence survival.
MF Segura, I Belitskaya-Lévy, AE Rose, J Zakrzewski, A Gaziel, D Hanniford, F Darvishian, I Osman, and E Hernando.
Clin Can Res 16(5): 1577-1586 (2010).
PMID: 2017923
Developing a multidisciplinary prospective melanoma biospecimen repository to advance translational research.
L Wich, H Hamilton, R Shapiro, A Pavlick, RS. Berman, D Polsky, J D. Goldberg, E Hernando, P. Manga, M Krogsgaard, H Kamino, F Darvishian, S Orlow, H Ostrer, N Bhardwaj, and I Osman.
Am J Transl Res. 1: 35-43 (2009).
PMID: 1996693
Aberrant miR-182 expression promotes melanoma metastasis by repressing Foxo3 and MITF.
MF Segura, D Hanniford, S Menendez, L Reavie, X Zou, S Alvarez-Diaz, J Zakrzewski, E Blochin, A Rose, D Bogunovic, D Polsky, JJ Wei, P Lee, I Belitskaya-Levy, N Bhardwaj, I Osman, and E Hernando.
PNAS 106 (6), 1814-1819 (2009).
PMID: 19188590